A businessman sinks $200 million into a special project to help fight brain cancer. As part of this project, medical biologist Susan McAlester rather naughtily figures out a way to genetically enlarge shark brains, so that cancer-battling enzymes can be harvested. However, the shark subjects become super smart and decide they don't much like being cooped up in pens and being stabbed with hypodermics, so they figure a way to break out and make for the open sea...

The fate of the world hangs in the balance in this explosive action thriller. Brace yourself for nonstop action and chilling suspense, because there's no turning back in this pulse-pounding sequel that takes you Behind Enemy Lines for another adrenaline-fueled adventure! When a team of U.S. Navy SEALs is assigned to destroy a North Korean missile site and avert a possible nuclear strike, failure is not an option. But the mission is abruptly aborted, stranding four soldiers in enemy territory. Now, in order to survive, they must defeat the rebel forces that threaten their lives, their allies and the entire free world!